KPV

KPV is a tripeptide (Lys-Pro-Val) with a molecular weight of approximately 342.4 g/mol. As the C-terminal fragment of α-MSH, KPV retains anti-inflammatory signaling properties without the melanocortin receptor-mediated pigmentation effects of the full-length parent hormone. This selectivity makes it a useful tool compound for researchers studying inflammation independently of melanogenesis.

Research applications include NF-κB signaling pathway studies, inflammatory bowel disease models, mucosal barrier integrity research, cytokine modulation assays, and comparative melanocortin pharmacology. KPV's lack of significant MC1R agonism distinguishes it from MT-2 and α-MSH in inflammation-specific research designs.

Every batch of KPV is synthesized using Solid-Phase Peptide Synthesis (SPPS) and purified via preparative HPLC to eliminate truncated sequences and synthesis byproducts. Final identity confirmation is performed via Electrospray Ionization Mass Spectrometry (ESI-MS), verifying exact molecular weight. Each lot ships with a Certificate of Analysis documenting purity exceeding 99%, giving researchers traceable, batch-specific verification before use in any laboratory protocol.

This product is strictly for research and laboratory use only. It is not approved by the FDA or any global regulatory body for human consumption, veterinary use, or therapeutic application. The purchaser assumes all responsibility for the proper handling, storage, and application of this compound. It must only be handled by qualified professionals in a controlled laboratory setting. By purchasing this product, you agree to abide by all local and international laws regarding the use of research chemicals.