

Epithalon (also known as Epitalon) is a research-grade synthetic tetrapeptide — Ala-Glu-Asp-Gly — derived from the endogenous polypeptide Epithalamin, which is produced by the pineal gland. It is one of the most studied longevity-focused research peptides in the published literature, with preclinical research examining its role in telomerase activation, telomere elongation, cellular senescence modulation, and age-associated neuroendocrine regulation. Each vial contains lyophilized Epithalon peptide, synthesized via SPPS and independently verified to ≥99% purity by third-party HPLC analysis. This compound is classified Research Use Only (RUO).
Epithalon is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly (AEDG) and a molecular weight of 390.35 g/mol. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology as a synthetic analogue of Epithalamin. The primary biological context driving research interest is its reported interaction with telomere homeostasis — specifically its putative capacity to stimulate telomerase (hTERT) expression and activity in somatic cell models.
The primary research applications center on cellular aging biology, telomere homeostasis research, and senescence pathway investigation. In vitro applications include hTERT gene expression assays, telomere length quantification assays, and senescence-associated beta-galactosidase staining studies. Comparative pharmacology studies contrasting Epithalon with other longevity-associated research peptides — such as SS-31 or MOTS-C — benefit from Epithalon's well-documented preclinical publication record.
Every batch undergoes independent third-party HPLC analysis prior to release. As a tetrapeptide, Epithalon is subject to specific synthesis quality considerations. Our ≥99% purity guarantee reflects the resolution of the complete chromatographic profile. All purity testing is conducted by certified third-party laboratories entirely independent of our production process.
This product is strictly for research and laboratory use only. It is not approved by the FDA or any global regulatory body for human consumption, veterinary use, or therapeutic application. The purchaser assumes all responsibility for the proper handling, storage, and application of this compound. It must only be handled by qualified professionals in a controlled laboratory setting. By purchasing this product, you agree to abide by all local and international laws regarding the use of research chemicals.

Tesamorelin + Ipamorelin blend — dual GHRH/GHSR research peptide combination. COA-verified, HPLC tested. Research use only.

Buy TB-500 research peptide — Thymosin Beta-4 active fragment. COA-verified, HPLC tested, 99%+ purity. Research use only.

Buy Sermorelin research peptide — GHRH(1-29) analog for growth hormone research. COA-verified, HPLC tested, 99%+ purity. Research use only.

Semax + Selank 10/10mg blend — dual nootropic neuropeptide research compound. COA-verified, HPLC tested. Research use only.
Find answers to common questions regarding storage, reconstitution, and testing guidelines for this specific compound.